Chemoresistance in prostate cancer cells is regulated by miRNAs and Hedgehog pathway.
Many prostate cancers relapse due to the generation of chemoresistance rendering first-line treatment drugs Wobbly Pot like paclitaxel (PTX) ineffective.The present study aims to determine the role of miRNAs and Hedgehog (Hh) pathway in chemoresistant prostate cancer and to evaluate the combination therapy using Hh inhibitor cyclopamine (CYA).Studi